Which traits are characteristic of the hepatitis b virus

Ahmed Shady. Ben Shamian. Nora V. Introduction: The estimated prevalence of chronic hepatitis B virus infection is 0. Accordingly, the aim of the present study was to characterize the patients with chronic hepatitis B at a community hospital in Brooklyn, New York. Methods: A retrospective chart review of patients with chronic hepatitis B seen in the hepatology clinic from to Data on country of origin, mode of transmission, hepatitis B serology and genotype, and liver histology were collected.

Results: Two-hundred and forty-seven patients with chronic hepatitis B of whom were men and were women, were identified. The average age was 46 years. The most common route of infection was sexual, followed by horizontal transmission. Genotype A was the most prevalent.

Conclusion : Chronic hepatitis B is one of the conditions commonly identified at a hepatology clinic in the North Brooklyn community; thus, screening practices to diagnose the infection and limit transmission by vaccination and education are warranted.

Around the world, over million people are infected with the chronic hepatitis B virus HBV ; of these, approximately , die yearly of its consequences. Accordingly, the aim of this study was to characterize the patients with chronic hepatitis B attended in a community hospital located in northern Brooklyn, and that serves a substantial number of patients from different parts of the world. This study was a retrospective review of charts from patients who had been seen at the hepatology clinic at least once between to , and whose medical records had been coded by ICD 10 as chronic hepatitis B.

The study was approved by the Institutional Review Board. Two-hundred and forty-seven patients were identified. The demographics are given in Table 1. The majority of patients was from Central and South America. The most common mode of transmission was unprotected sexual intercourse; however, in patients the route of transmission was not documented.

Comorbid conditions included hypertension, diabetes mellitus, and human immunodeficiency virus infection. One patient was co-infected with the delta hepatitis virus. In the majority of patients, serum activity of liver transaminases was below two times the upper limit of normal, considered to reflect minimal or no inflammatory activity.

Mutations were detected in of Hepatitis B virus: Screening and diagnosis. Mantzoukis K, et al. Pharmacological interventions for acute hepatitis B infection. Cochrane Database of Systematic Reviews.

Hepatitis B FAQs for the public. Centers for Disease Control and Prevention. Hepatitis B. World Health Organization. Lok AS, et al. Hepatitis B cure: From discovery to regulatory approval. Journal of Hepatology. Feldman M, et al. Saunders Elsevier; Accessed July 22, National Institutes of Health. Interferon Alfa-2b. Zheng Zeng. Potential conflicts of interest: none reported. Select Format Select format. Permissions Icon Permissions. Table 1. Characteristic No.

Abbreviations: SD, standard deviation. Open in new tab. Table 2. Prospective study of hepatocellular carcinoma and liver cirrhosis in asymptomatic chronic hepatitis B virus carriers. Google Scholar Crossref. Search ADS. The long-term serological course of asymptomatic hepatitis B virus carriers and the development of primary hepatocellular carcinoma. HBsAg seroclearance in asymptomatic carriers of high endemic areas: appreciably high rates during a long-term follow-up.

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A population-based study to investigate host genetic factors associated with hepatitis B infection and pathogenesis in the Chinese population.

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Tissue-specific genetic control of splicing: implications for the study of complex traits. Predominant T-helper 1 cytokine profile of hepatitis B virus nucleocapsid-specific T cells in acute self-limited hepatitis B. Differential genetic determination of immune responsiveness to hepatitis B surface antigen and to hepatitis A virus: a vaccination study in twins. All rights reserved. For Permissions, please e-mail: journals.

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